Last Software Update

v2.31.9 (Dec 16, 2016)


MAKER is a portable and easily configurable genome annotation pipeline. Its purpose is to allow smaller eukaryotic and prokaryotic genome projects to independently annotate their genomes and to create genome databases. MAKER identifies repeats, aligns ESTs and proteins to a genome, produces ab-initio gene predictions and automatically synthesizes these data into gene annotations having evidence-based quality values. MAKER is also easily trainable: outputs of preliminary runs can be used to automatically retrain its gene prediction algorithm, producing higher quality gene-models on seusequent runs. MAKER's inputs are minimal and its ouputs can be directly loaded into a GMOD database. They can also be viewed in the Apollo genome browser; this feature of MAKER provides an easy means to annotate, view and edit individual contigs and BACs without the overhead of a database. MAKER should prove especially useful for emerging model organism projects with minimal bioinformatics expertise and computer resources.


MAKER is available for academic use under either the Artistic License 2.0 developed by the Perl Foundation or the GNU General Public License developed by the Free Software Foundation.

MAKER is not available for commercial use without a license. Those wishing to license MAKER for commercial use should contact Aaron Duffy at the University of Utah TVC to discuss your needs.


To download MAKER for academic research use or to access an existing academic or commercial license, please visit our Registration Page.

To download the current MAKER distribution for academic research use we ask you to register with a valid e-mail address. We are asking for this information so that we can keep track of new users for generating usage reports for funding agencies. Your e-mail address will be used for creating an anonymous aggregate count of MAKER users and will not by used for any other purposes. Your e-mail will not be shared or made public in any way and we won't even subscribe you to our mailing list - you can do that seperately.

Demo Web Interface

A version of MAKER has been installed online with a GUI that users can try via a web browser. The MAKER Web Annotation Service (MWAS) can be accessed using the link below. This is one way to try out the capabilities of MAKER before installing it locally. Please be aware this version is for demo and educational purposes, so job submission size is limited. You will want to install MAKER locally for production purposes.

Access MWAS Demo


Documentation for the MAKER project can be found included in the MAKER distribution, and is included on this website as well with links below.

MAKER Installation

MAKER Documentation

MAKER Tutorial at GMOD


Support for MAKER is provided by a wiki, a collection of archived posts to the mailing list, and the mailing list itself. Please check for answers to your questions using those sources, in that order.
Please join the mailing list and become a member of the MAKER community.

Check out this instructional MAKER wiki.

The maker-devel mailing list is archived on Google Groups which has archive searching capabilities. Search for answers to common questions/problems there.

Subscribe/Unsubscribe to the maker-devel mailing list to get updates on MAKER as well as ask questions not covered in the wiki or maker-devel archives.

Send mail to the maker-devel mailing list (members only - sign up above).


Having fun with MAKER? Proudly sport your new annotation addiction with some MAKER bling!